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EB病毒的概述

时间:2019-07-16 来源:《当代畜禽养殖业》杂志 作者:admin 点击:

  摘要:EB病毒(Epstein Barr virus, EBV),又称人类疱疹病毒(Human herpes virus 4,HHV-4),它只能在B淋巴细胞中增殖,其感染与多种疾病有关。根据感染后是否产生有感染性的病毒子代,可分为增生性感染和非增生性感染:与增殖性感染相关的抗原有早期抗原、膜抗原和衣壳抗原,已确定的非增殖性感染抗原有核抗原和潜伏感染蛋白。研究EBV的抗原及抗体,对揭示EBV与鼻咽癌的关系以及鼻咽癌的早期诊断均有重要意义。

  关键词:EB病毒; 抗原; 鼻咽癌;

  参考文献

  [1]Serological diagnosis of Epstein-Barr virus infection: Problems and solutions[J]. Massimo De Paschale,Pierangelo Clerici. World Journal of Virology. 2012(01)

  [2]鼻咽癌细胞系 SUNE 中 EBV-LMP1 基因对上皮细胞增殖的影响[J]. 陈宜芳,郭辉玉,汪慧民,李满枝. 肿瘤. 1999(01)

  [3]Epstein-Barr病毒膜抗原在昆虫细胞sf9中的表达、纯化及其免疫原性[J]. 刘展,周为民,谷淑燕. 中华实验和临床病毒学杂志. 1996(04)

  国际期刊数据库 共6条

  [1]Epstein‐Barr virus nuclear antigen 1 (EBNA1) protein induction of epithelial‐mesenchymal transition in nasopharyngeal carcinoma cells[J] . Lu Wang,Wen‐Dong Tian,Xia Xu,Biao Nie,Juan Lu,Xiong Liu,Bao Zhang,Qi Dong,John B. Sunwoo,Gang Li,Xiang‐Ping Li. Cancer . 2014 (3)

  [2]X-linked lymphoproliferative syndromes and related autosomal recessive disorders[J] . André Veillette,Luis-Alberto Pérez-Quintero,Sylvain Latour. Current Opinion in Allergy and Clinical Immunology . 2013 (6)

  [3]A Genome-Wide Integrative Genomic Study Localizes Genetic Factors Influencing Antibodies against Epstein-Barr Virus Nuclear Antigen 1 (EBNA-1)[J] . Rohina Rubicz,Robert Yolken,Eugene Drigalenko,Melanie A. Carless,Thomas D. Dyer,Lara Bauman,Phillip E. Melton,Jack W. Kent,John B. Harley,Joanne E. Curran,Matthew P. Johnson,Shelley A. Cole,Laura Almasy,Eric K. Moses,Nikhil V. Dhurandhar,Ellen Kraig,John Blangero,Charles T. Leach,Harald H. H. G?ring. PLOS Genetics . 2013 (1)

  [4]Mycoplasma pneumoniae preceding Lemierre’s syndrome due to Fusobacterium nucleatum complicated by acute Epstein–Barr virus (EBV) infectious mononucleosis in an immunocompetent host[J] . Natalie C. Klein,Andrew Petelin,Burke A. Cunha. Heart & Lung - The Journal of Acute and Critical Care . 2012

  [5]Regulation and dysregulation of Epstein–Barr virus latency: Implications for the development of autoimmune diseases[J] . Hans Helmut Niller,Hans Wolf,Janos Minarovits. Autoimmunity . 2008 (4)

  [6]Epstein-Barr virus-targeted immunotherapy for nasopharyngeal carcinoma[J] . Amine Masmoudi,Nabil Toumi,Afef Khanfir,Lamia Kallel-Slimi,Jamel Daoud,Hela Karray,Mounir Frikha. Cancer Treatment Reviews . 2007 (6)

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